61962

Betaine

BioUltra, ≥99.0% (NT)

• Synonym(s): (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine
• Linear Formula: (CH₃)₃N⁺CH₂COO^-
• CAS Number: 107-43-7
• Molecular Weight: 117.15
• Beilstein: 3537113
• EC Number: 203-490-6
• MDL number: MFCD00012123
• UNSPSC Code: 41116107
• PubChem Substance ID: 57651874
• NACRES: NA.25

Properties

• product line: BioUltra
• Assay: ≥99.0% (NT)
• impurities: insoluble matters, passes filter test
• solubility: methanol: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤200 mg/kg; sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: ≤0.05 at 280 nm in methanol at 1 M; ≤0.09 at 260 nm in methanol at 1 M
• SMILES string: C[N+](C)(C)CC([O-])=O
• InChI: 1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
• InChI key: KWIUHFFTVRNATP-UHFFFAOYSA-N

Description

General description

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Application

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.

Biochem/physiol Actions

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves