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12266

Sigma-Aldrich

N-[4-(2-Benzimidazolyl)phenyl]maleimide

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Synonym(s):

BIPM

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About This Item

Empirical Formula (Hill Notation):
C17H11N3O2
CAS Number:
27030-97-3
Molecular Weight:
289.29
Beilstein:
755407
EC Number:
248-173-3
MDL number:
MFCD00042767
UNSPSC Code:
12352200
PubChem Substance ID:
57646978

product line

BioReagent

Assay

≥98.0% (HPLC)

form

solid

solubility

H2O: soluble
acetone: soluble

fluorescence

λex 315 nm; λem 365 nm (after derivatization with 2-mercaptoethanol)

suitability

suitable for fluorescence

SMILES string

O=C1C=CC(=O)N1c2ccc(cc2)-c3nc4ccccc4[nH]3

InChI

1S/C17H11N3O2/c21-15-9-10-16(22)20(15)12-7-5-11(6-8-12)17-18-13-3-1-2-4-14(13)19-17/h1-10H,(H,18,19)

InChI key

NZDOXVCRXDAVII-UHFFFAOYSA-N

Other Notes

Fluorescent probe in proteins, used for microfluorometry of thiol compounds (detection limit: 10-6 m thiol conc.); Review

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K Taniguchi et al.
The Journal of biological chemistry, 258(11), 6927-6931 (1983-06-10)
The addition of ATP to (Na+,K+)-ATPase (EC 3.6.1.3) of pig kidney modified with N-[p-(2-benzimidazolyl)phenyl]maleimide induced three different modes of fluorescence change: positive, biphasic, and negative, which were observed, respectively, in the presence of Mg2+ with 16 or 160, 320 or
Robert J W Brewin et al.
Sensors (Basel, Switzerland), 19(4) (2019-03-01)
Two expanding areas of science and technology are citizen science and three-dimensional (3D) printing. Citizen science has a proven capability to generate reliable data and contribute to unexpected scientific discovery. It can put science into the hands of the citizens
K Taniguchi et al.
Journal of biochemistry, 109(2), 299-306 (1991-02-01)
Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration of Na+ with a Hill coefficient of nh = 0.77 with Kh = 231 mM.
Luciano Giromini et al.
Journal of mental health (Abingdon, England), 26(6), 523-529 (2017-06-27)
Emotional intelligence (EI) is a field of study that is receiving increasingly attention in the literature, due to its relevance to a series of aspects of human psychological and social functioning. This study used archival data from an Italian sample
P K Jha et al.
Biochemistry, 35(34), 11026-11035 (1996-08-27)
Contraction of vertebrate striated muscle is regulated by the strong Ca(2+)-dependent interaction between troponin I (TnI) and troponin C (TnC). To critically evaluate this interaction, we generated four recombinant deletion fragments of rabbit fast skeletal TnI: the NH2-terminal fragment (TnI1-94)
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