111R-1

CD11c (EP157) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP157, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (111R-14); vial of 0.1 mL concentrate Research Use Only (111R-14-RUO); vial of 0.5 mL concentrate (111R-15); vial of 1.0 mL concentrate (111R-16); vial of 1.0 mL concentrate Research Use Only (111R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (111R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (111R-17); vial of 7.0 mL pre-dilute ready-to-use (111R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (111R-18-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)
• isotype: IgG
• control: hairy cell leukemia, spleen, tonsil
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... ITGAX(3687)

Description

General description

CD11c is an adhesion receptor of the leukocyte function-associated family of molecules. This cell surface antigen is normally expressed on granulocytes, monocytes, natural killer cells, macrophages, and small populations of T- and B-lymphocytes. Anti-CD11c detects a formalin-resistant epitope of CD11c expressed in hairy cell leukemia (HCL). HCL is a distinctive yet uncommon chronic B-cell lymphoproliferative disorder, predominantly involving the bone marrow and spleen. Besides being consistently expressed in HCL, CD11c is rarely detected in lymphomas; such as small lymphocytic lymphoma (SLL), and nodal and extranodal marginal zone lymphoma (MZL).

Quality

IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable