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Y101

Supelco

YS-035 hydrochloride

analytical standard, for drug analysis

Synonym(s):

N-(-2-[3,4-Dimethoxyphenyl]ethyl)-3,4-dimethoxy-N-methylbenzeneethanamine

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About This Item

Empirical Formula (Hill Notation):
C21H29NO4 · HCl
CAS Number:
33978-72-2
Molecular Weight:
395.92
MDL number:
MFCD00153884
UNSPSC Code:
41116107
PubChem Substance ID:
329831585
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl[H].COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC

InChI

1S/C21H29NO4.ClH/c1-22(12-10-16-6-8-18(23-2)20(14-16)25-4)13-11-17-7-9-19(24-3)21(15-17)26-5;/h6-9,14-15H,10-13H2,1-5H3;1H

InChI key

GYBONEHHSUABAO-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
038H4697

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R Deana et al.
The Biochemical journal, 218(3), 899-905 (1984-03-15)
Compound YS 035 [NN-bis-(3,4-dimethoxyphenethyl)-N-methylamine] is a new synthetic compound capable of inhibiting Ca2+ uptake by different cells. The inhibition of Ca2+ uptake by muscle cells isolated from chicken embryo is dose-dependent in the compound YS 035 concentration range 10-30 microM.
S L Mironov et al.
The European journal of neuroscience, 12(2), 520-526 (2000-03-11)
A hyperpolarization-activated current, Ih, is often implied in pacemaker-like depolarizations during rhythmic oscillatory activity. We describe Ih in the isolated respiratory centre of immature mice (P6-P11). Ih was recorded in 15% (22/146) of all inspiratory neurons examined. The mean half-maximal
F Berger et al.
Naunyn-Schmiedeberg's archives of pharmacology, 344(6), 653-661 (1991-12-01)
The electrophysiologic mode of action and potency of the verapamil derivative YS 035 (N,N-bis-(3,4-dimethoxyphenethyl)-N-methyl amine) were investigated in sheep cardiac Purkinje fibres. Action potential duration measured at a repolarization level of -60 mV (APD-60) and membrane currents recorded with the
P C Levesque et al.
Toxicology and applied pharmacology, 94(1), 55-65 (1988-06-15)
Agents known to disrupt intraterminal Ca2+ buffering, N,N-dimethylamino-8-octyl-3,4,5-trimethoxybenzoate (TMB-8), 25 microM; caffeine, 7.5 mM; N,N-bis(3,4-dimethoxyphenethyl)-N-methylamine (YS035), 180 microM; ouabain, 200 microM; and dantrolene, 50 microM, were tested for the ability to alter effects of methyl mercury (MeHg) on spontaneous quantal
Carbamazepine and L-type calcium channel inhibitors: a binding assay study.
E T Ngan et al.
Biological psychiatry, 39(11), 979-981 (1996-06-01)
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