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SMB01345

Sigma-Aldrich

N-Methyl-2-pyridone-5-carboxamide

Synonym(s):

1,6-Dihydro-1-methyl-6 -oxonicotinamide, 1-Methyl-5-carboxylamide-2-pyridone, 2-Py, 2PY, 3-Carbamoyl-1-methyl-6-pyridone, N1-Methyl-2-pyridone-5-carboxamide, Me2PY, Met2PY, Nedifloramide, Nudifloramide

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About This Item

Empirical Formula (Hill Notation):
C7H8N2O2
CAS Number:
Molecular Weight:
152.15
MDL number:
UNSPSC Code:
41116105
NACRES:
NA.77
Pricing and availability is not currently available.

Assay

≥95% (HPLC)

Quality Level

form

solid

mp

210—21.5 °C

SMILES string

[n]1([c](ccc(c1)C(=O)N)=O)C

InChI

1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)

InChI key

JLQSXXWTCJPCBC-UHFFFAOYSA-N

General description

N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin.

Application

Metabolomics research

Other Notes

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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