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S5016

Sigma-Aldrich

Sucrose

ACS reagent

Synonym(s):

α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
90825
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

sugar cane

Quality Level

grade

ACS reagent

form

powder or crystals

optical activity

[α]25/D +66.3 to +66.8°(lit.)

technique(s)

HPLC: suitable
cryopreservation: suitable
immunohistochemistry: suitable

impurities

≤0.0008 meq/g Titratable acid
≤0.005% Insoluble matter
≤0.05% Invert sugar

ign. residue

≤0.01%

loss

≤0.03% loss on drying, 105°C

color

white

useful pH range

5.5-7.5 (25 °C, 342 g/L)

mp

185-187 °C (lit.)

solubility

soluble 342 g/L at 20 °C (completely)

anion traces

chloride (Cl-): ≤0.005%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

application(s)

agriculture
cell analysis
life science and biopharma
metabolomics

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

CZMRCDWAGMRECN-UGDNZRGBSA-N

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General description

Sucrose, a disaccharide consisting of glucose and fructose, serves as an energy source in numerous biological processes. In cell culture, sucrose functions as a cryoprotectant, preserving cell viability during freezing and thawing while also helping to maintain osmotic balance and enhance cell survival. Moreover, sucrose finds utility as a supplement in plant, insect, and bacterial culture media, and it is applied in various enzymatic assays. In biomedical research, it plays a role as an osmolyte, an algal metabolite, a Saccharomyces cerevisiae metabolite, an E. coli metabolite, and a mouse metabolite.

Application

Sucrose has been used
  • in a growth medium to study the molecular and biochemical aspects of plant-pathogen interactions and plant immune responses
  • as a cryoprotectant in a study involving antibiotic-induced changes to the gut microbiota and their effects on neuroimmune interactions

Biochem/physiol Actions

Sucrose serves as a vital energy source, undergoing metabolic conversion to produce adenosine triphosphate (ATP) for cellular functions and cellular respiration. In plant biology, sucrose is central to photosynthesis and acts as a storage carbohydrate in various plant parts. In Cell Biology, it helps maintain osmotic balance in cells, acts as a cryoprotectant in laboratory settings, and participates in biosynthesis, leading to the formation of secondary metabolites.

Features and Benefits

  • Suitable for cell biology and biochemical research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for anion and cation traces
  • ACS grade sucrose, sourced from sugar cane

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The non-receptor tyrosine kinase c-Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and potential activating mutations

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