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63575

Sigma-Aldrich

D-Mannosamine hydrochloride

≥98.0% (TLC)

Synonym(s):

2-Amino-2-deoxy-D-mannose hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
5505-63-5
Molecular Weight:
215.63
Beilstein:
3914860
EC Number:
226-847-8
MDL number:
MFCD00064557
UNSPSC Code:
12352201

Assay

≥98.0% (TLC)

optical activity

[α]20/D −3.7±0.5°, c = 2% in H2O

mp

168 °C (dec.) (lit.)
170-175 °C (dec.)

solubility

H2O: 0.1 g/mL, clear, colorless

SMILES string

Cl[H].N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3+,4-,5-,6?;/m1./s1

InChI key

QKPLRMLTKYXDST-OHXGPSCHSA-N

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Description
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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Juan M Irache et al.
Frontiers in bioscience (Scholar edition), 2, 876-890 (2010-06-03)
In the last years, many efforts have been directed toward the enhancement of vaccine delivery by using polymeric nanoparticles as adjuvants for mucosal immunization. However, conventional nanoparticles usually display a low capability to target specific sites within the gut and
Pongthep Pukanud et al.
Drug delivery, 16(5), 289-294 (2009-06-23)
The aim of this study was to develop mannosylated liposomes as bioadhesive carriers for oral drug delivery. Two kinds of acyclovir (ACV)-entrapped mannosylated liposomes, i.e. ManN-ACV-lip and PAM-ACV-lip, were prepared by the use of mannosamine HCl (ManN) and p-aminophenyl-alpha-D-mannopyranoside (PAM)
Yu-Shen Cheng et al.
Analytical biochemistry, 408(1), 160-162 (2010-08-25)
A 96-well plate method was developed for analysis of total hexosamine content in biological samples. Four hexosamine monomer derivatives-glucosamine hydrochloride, glucosamine sulfate, galactosamine hydrochloride, and mannosamine hydrochloride-were examined for the linearity of their spectra in the concentration range specified in
Mohit P Mathew et al.
Bioorganic & medicinal chemistry letters, 22(22), 6929-6933 (2012-10-09)
This report provides a synopsis of the esterase processing of short chain fatty acid (SCFA)-derivatized hexosamine analogs used in metabolic glycoengineering by demonstrating that the extracellular hydrolysis of these compounds is comparatively slow (e.g., with a t(1/2) of ∼4 h
Alyaa Ibrahim et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 13(2), 128-135 (2010-09-08)
An improved HPLC method with fluorescence detection was developed and validated for determination of glucosamine in human and rat biological samples. Aliquot of 0.1 mL plasma was spiked with mannosamine HCl as the internal standard (IS); proteins were precipitated with
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