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45753

Supelco

Flusilazole

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H15F2N3Si
CAS Number:
85509-19-9
Molecular Weight:
315.39
Beilstein:
5824097
MDL number:
MFCD01076615
UNSPSC Code:
41116107
PubChem Substance ID:
329756936
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

C[Si](Cn1cncn1)(c2ccc(F)cc2)c3ccc(F)cc3

InChI

1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3

InChI key

FQKUGOMFVDPBIZ-UHFFFAOYSA-N

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General description

Flusilazole is an organosilicon fungicide, which belongs to the class of sterol demethylation inhibitors. Its mode of action involves the inhibition of lanosterol 1,4-α-demethylation in fungal sterol biosynthesis.

Application

Flusilazole may be used as a reference standard for the determination of flusilazole in water samples using solid-phase extraction (SPE) method using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H302,H351,H360D,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3244
BCBZ0782
BCBV0143
SZBC320XV
SZB8294XV

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Determination of pyrazole and pyrrole pesticides in environmental water samples by solid-phase extraction using multi-walled carbon nanotubes as adsorbent coupled with high-performance liquid chromatography.
Ma J, et al.
Journal of Chromatographic Science, 53(2), 380-384 (2014)
Sensitivity of Venturia inaequalis isolates from British Columbia to flusilazole and myclobutanil.
Sholberg LP and Haag DP
Canadian Journal of Plant Pathology, 15(2), 102-106 (1993)
E Menegola et al.
Reproductive toxicology (Elmsford, N.Y.), 15(4), 421-427 (2001-08-08)
Triazole-derivatives are antimycotics used in agriculture as well as in clinical and veterinary therapy. The aim of the present work is the in vitro comparative study of the teratogenic activity of triazole (the parental compound), flusilazole (an agricultural triazole mono-derivative
J J Anderson et al.
Journal of agricultural and food chemistry, 47(6), 2439-2446 (2000-05-04)
[Phenyl(U)-(14)C] and [triazole(3)-(14)C]flusilazole ([(bis 4-fluorophenyl)]methyl(1H-1,2,4-triazole-1-ylmethyl)silane; I) were extensively metabolized when fed to lactating goats (Capra hircus). The primary metabolites identified in goat tissues and milk were bis(4-fluorophenyl)(methyl)silanol (II) and 1H-1,2,4-triazole (III). Concentrations of total radiolabeled residues in the milk ranged
Dorien A M van Dartel et al.
Toxicology and applied pharmacology, 251(2), 110-118 (2011-01-05)
The murine embryonic stem cell test (EST) is designed to evaluate developmental toxicity based on compound-induced inhibition of embryonic stem cell (ESC) differentiation into cardiomyocytes. The addition of transcriptomic evaluation within the EST may result in enhanced predictability and improved
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