598250

THP

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.

• Synonym(s): THP, Tris(hydroxypropyl)phosphine
• Empirical Formula (Hill Notation): C₉H₂₁O₃P
• CAS Number: 4706-17-6
• Molecular Weight: 208.24
• MDL number: MFCD00269835
• UNSPSC Code: 12352128
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥80% (³¹P-NMR)
• form: viscous liquid
• reaction suitability: reagent type: reductant
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• color: colorless
• solubility: water: 20 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C9H21O3P/c10-4-1-7-13(8-2-5-11)9-3-6-12/h10-12H,1-9H2
• InChI key: YICAEXQYKBMDNH-UHFFFAOYSA-N

Description

General description

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT. THP is comparable with TCEP (Cat. No. 580560) as a reducing agent. Its reduction capacity against oxidized glutathione is 0.232 meq/g (Note: TCEP has a reduction capacity of 0.182 meq/g). THP is also more resistant to air oxidation as compared to DTT.

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT. THP is comparable with TCEP (Cat. No. 580560) as a reducing agent. Its reduction capacity against oxidized glutathione is 0.232 meq/g compared to TCEP with a reduction capacity of 0.182 meq/g. THP is also more resistant to air oxidation compared to DTT.

Packaging

Packaged under inert gas

Warning

Toxicity: Corrosive (L)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable