420112

JAK3 Inhibitor, Negative Control - CAS 153437-07-1 - Calbiochem

The JAK3 Inhibitor, Negative Control, also referenced under CAS 153437-07-1, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Synonym(s): JAK3 Inhibitor, Negative Control - CAS 153437-07-1 - Calbiochem, 4-Phenylamino-6,7-dimethoxyquinazoline, HCl, WHI-P258, HCl
• Empirical Formula (Hill Notation): C₁₆H₁₅N₃O₂ · xHCl
• CAS Number: 153437-07-1
• Molecular Weight: 281.31 (free base basis)
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥92% (HPLC)
• form: solid
• potency: <300 μM IC₅₀
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: pale yellow
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C

Description

General description

A useful negative control for JAK3 Inhibitors (Cat. Nos. 420101, 420104, and 420106; IC₅₀ >300 µM).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A negative control for JAK3 inhibitors

Product competes with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 year at 4°C.

Other Notes

Sudbeck, E.A., et al. 1999. Clin. Cancer Res. 5, 1569.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10-13 - German Storage Class 10 to 13