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A-040

Supelco

Aminorex solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
2207-50-3
Molecular Weight:
162.19
UNSPSC Code:
41116107

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

NC1=NCC(O1)c2ccccc2

InChI

1S/C9H10N2O/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)

InChI key

SYAKTDIEAPMBAL-UHFFFAOYSA-N

General description

An analytical reference standard suitable for use in LC/MS or GC/MS methods for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research applications. Aminorex is an anorectic stimulant drug and appetite suppressant marketed under the names Menocil and Apiquel®. The drug was retired from the market after it was found to cause pulmonary hypertension.

Legal Information

Apiquel is a registered trademark of Puricorp Holdings LLC
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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S B Gross et al.
Reviews in cardiovascular medicine, 1(2), 80-89 (2002-11-29)
Three years after the withdrawal of fenfluramine and dexfenfluramine from the market, the magnitude and prevalence of their deleterious cardiopulmonary effects remain undetermined. The links between these anorexigens and valvular heart disease and primary pulmonary hypertension, however, are clearly established.
Steven B Karch et al.
International journal of cardiology, 158(3), 344-346 (2011-07-19)
Levamisole is found in more than 80% of illicit cocaine seized within United States borders. Percentages are somewhat lower in Europe. In 2009, controlled in vivo studies demonstrated that horses metabolize levamisole to aminorex. Earlier this year our laboratory demonstrated
Two different drug-induced pulmonary complications in a patient suffering from rheumatoid arthritis.
B F Leeb et al.
British journal of rheumatology, 37(5), 586-587 (1998-07-03)
R M Tuder et al.
American journal of respiratory and critical care medicine, 158(6), 1999-2001 (1998-12-16)
Anorexigens such as aminorex fumarate and dexfenfluramine are associated with the development of severe pulmonary hypertension (PH), which clinically and histopathologically is considered indistinguishable from idiopathic or primary pulmonary hypertension (PPH). For the current study, we asked whether anorexigen-associated PH
A century of pulmonary hemodynamics.
Alfred P Fishman
American journal of respiratory and critical care medicine, 170(2), 109-113 (2004-07-10)
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