810240P
Avanti
TopFluor™ TMR PA
Avanti Research™ - A Croda Brand 810240P, powder
Synonym(s):
1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphate (ammonium salt)
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About This Item
Empirical Formula (Hill Notation):
C48H74 BF2N4 O10P
CAS Number:
Molecular Weight:
946.90
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810240P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810240P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidic acid (PA) is a diacyl-glycerophospholipid that consists of a glycerol and an alcohol moiety, having two fatty acids and a phosphate group esterified at positions 1, 2, and 3, respectively.
Biochem/physiol Actions
Phosphatidic acid (PA) is a signaling molecule that is synthesized in the endoplasmic reticulum (ER). It is transported to the mitochondrial outer membrane to stimulate mitofusin (Mfn)-mediated fusion. PA is a major intermediate metabolite involved in the synthesis of membrane glycerophospholipids, which include phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylserine (PS).
Packaging
5 mL Amber Glass Screw Cap Vial (810240P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders, 28(1), 67-76 (2015)
Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Multifunctional Systems for Combined Delivery Biosensing and Diagnostics, 28(1), 67-76 (2020)
Shoichiro Kameoka et al.
Trends in cell biology, 28(1), 67-76 (2017-09-16)
Membrane organelles comprise both proteins and lipids. Remodeling of these membrane structures is controlled by interactions between specific proteins and lipids. Mitochondrial structure and function depend on regulated fusion and the division of both the outer and inner membranes. Here
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