Trilayer polymer films consisting of a thermoresponsive hydrogel, poly(diethyl acrylamide) (PDEAM), sandwiched by rigid layers of a glassy polymer, poly(para-methylstyrene) (PpMS), patterned into parallel striped features are prepared and used to drive temperature-responsive reversible anisotropic expansion. Significant swelling occurs along
Pectin based micro/nanocarriers display promising properties for biomedical applications. In this study, thermo/pH-responsive chitosan coated pectin-graft-poly(N,N-diethyl acrylamide) (Pec-g-PDEAAm/CS) microcarriers containing 5-Fluorouracil (5-FU) as a model drug were developed. The structure, thermal stability and surface morphology of 5-FU-loaded microcarriers were investigated
Colloids and surfaces. B, Biointerfaces, 136, 1182-1192 (2015-11-23)
Salecan is a water-soluble microbial polysaccharide produced by Agrobacterium sp. ZX09, a salt-tolerant strain isolated from a soil sample in our laboratory. Previous work inspired us salecan is a good candidate to fabricate hydrogels. Poly(N,N-diethylacrylamide) is one type of thermo
A series of semi-interpenetrating polymer network (semi-IPN) hydrogels based on N,N'-diethylacrylamide (DEA) and itaconamic acid (IAM) were synthesized by changing the molar ratio of linear copolymer P(DEA-co-IAM) and DEA monomer. Linear copolymer P(DEA-co-IAM) was introduced into a solution of DEA
Many medical and biotechnological processes rely on controlling and manipulating the molecular-recognition capabilities of proteins. This can be achieved using small molecules capable of competing for protein binding or by changing environmental parameters that affect protein structure and hence binding.
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