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630586

Sigma-Aldrich

2′-Hydroxy-4′,6′-dimethoxyacetophenone

97%

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5 G
MXP 1,411.00

MXP 1,411.00


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5 G
MXP 1,411.00

About This Item

Empirical Formula (Hill Notation):
C10H12O4
CAS Number:
Molecular Weight:
196.20
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

MXP 1,411.00


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Request a Bulk Order

Quality Level

Assay

97%

form

solid

mp

80-84 °C (lit.)

functional group

ketone

SMILES string

COc1cc(O)c(C(C)=O)c(OC)c1

InChI

1S/C10H12O4/c1-6(11)10-8(12)4-7(13-2)5-9(10)14-3/h4-5,12H,1-3H3

InChI key

FBUBVLUPUDBFME-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Rodrigo dos Santos et al.
Archiv der Pharmazie, 339(5), 227-237 (2006-03-31)
Semi-empirical molecular orbital calculations at AM1 level were done with the aim to investigate the structure-activity relationships of antispasmodic activities of ten 2-(X-benzyloxy)-4,6-dimethoxyacetophenones with X = H, 4'-F, 4'-NO2, 4'-CH3, 4'-Cl, 3',4'-(CH3)2, 4'-OCH3, 4'-Br, 4'-OCH2C6H5, and 4'-C(CH3)3, against acetylcholine-induced contraction
J B Calixto et al.
Planta medica, 56(1), 31-35 (1990-02-01)
The inhibitory action of the major constituent of Sebastiania schottiana (Euphorbiaceae), 2-hydroxy-4,6-dimethoxyacetophenone (xanthoxyline) on contractions induced by agonists and electrical stimulation of smooth and cardiac muscle preparations was analysed. Xanthoxyline (30 to 300 microM) inhibited contractions of the rat uterus
Paula Boeck et al.
Bioorganic & medicinal chemistry, 14(5), 1538-1545 (2006-01-03)
Eighteen analogues of an active natural chalcone were synthesized using xanthoxyline and some derivatives, and these analogues were tested for selective activity against both promastigotes and intracellular amastigotes of Leishmania amazonensis in vitro. Three analogues (10, 12, and 19) containing
Fátima de Campos-Buzzi et al.
Archiv der Pharmazie, 339(7), 361-365 (2006-07-14)
A wide variety of noxious stimuli are known to induce a sensation of pain evoked in a remote region of the body. Here, we show that chalcones can inhibit the pain provoked by the administration of an intraperitoneal acetic acid
Z R Vaz et al.
The Journal of pharmacology and experimental therapeutics, 278(1), 304-312 (1996-07-01)
The antinociceptive effect of the novel xanthoxyline derivative 2-(4-bromobenzoyl)-3-methyl-4-6-dimethoxy benzofuran) (BMDB), given i.p., p.o., s.c., subplantarly, intrathecally or by i.c.v. routes was assessed in five models of chemical and thermal nociception in mice, namely acetic acid-induced abdominal constriction, formalin and

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