This product is intended for research use only and is not food grade. Therefore it is not recommended for a fruit coating application.
448869
Chitosan
low molecular weight
Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
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50 G
MXP 1,979.00
250 G
MXP 6,835.00
About This Item
Recommended Products
Quality Level
form
powder
mol wt
50,000-190,000 Da (based on viscosity)
viscosity
20-300 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)
solubility
dilute aqueous acid: soluble
SMILES string
N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](
InChI
1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1
InChI key
FLASNYPZGWUPSU-SICDJOISSA-N
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Application
Chitosan may be used as a flocculant, in protein precipitation, encapsulating agent and aqueous thickener.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.
Features and Benefits
Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.
Physical form
75-85% deacetylated
Storage Class Code
11 - Combustible Solids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Lot/Batch Number
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Tsung-Lin Yang et al.
Journal of cellular and molecular medicine, 13(9A), 2853-2863 (2008-07-17)
Chitosan is a widely used biocompatible biomaterial in the tissue regeneration, but its utility and application in the tissue morphogenesis of salivary gland remains unclear. The study aimed to explore the effects of chitosan on the epithelial morphogenesis of submandibular
Ming-Hui Yang et al.
BioMed research international, 2014, 789591-789591 (2014-04-24)
Chitosan nanoparticle, a biocompatible material, was used as a potential drug delivery system widely. Our current investigation studies were the bioeffects of the chitosan nanoparticle uptake by liver cells. In this experiment, the characterizations of chitosan nanoparticles were measured by
Ajay Vijayakumar et al.
AAPS PharmSciTech, 18(3), 875-883 (2016-07-03)
The objective of this study was to formulate and characterize properties of solid lipid nanoparticle (SLN) dispersion containing quercetin. SLN was prepared by ultrasonication method using tripalmitin and lecithin as lipid core and then the surface was coated with chitosan.
Mohammad Ali Khosravi Zanjani et al.
Iranian journal of pharmaceutical research : IJPR, 13(3), 843-852 (2014-10-03)
Microencapsulation as one of the most modern methods has considerable effects on probiotic survival. In this study Lactobacillus casei (ATCC 39392) and Bifidobacterium bifidum (ATCC 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and
Wei-Hsuan Lo et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-07)
(1) Background: Few antifungal drugs are currently available, and drug-resistant strains have rapidly emerged. Thus, the aim of this study is to evaluate the effectiveness of the antifungal activity from a combinational treatment of chitosan with a clinical antifungal drug
Articles
Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.
Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.
Polymers, natural or synthetic, are vital in medical advancements, contributing to device and pharmaceutical development in therapy.
Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.
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Can i use this Chitosan for fruit coating?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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We need to confirm if this Chitosan (Catalog #448869) is of animal origin (shellfish) or synthetic.
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The source information is located on the Certificate of Origin and may vary from lot to lot. Recent lot shows the source of this product is from the shells of Pandalus Borealis, Cold Water Shrimp.
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What is the molecular weight (Mw) of products 448869, 448877, or 419419?
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The molecular weight (Mw) of products 448869, 448877, and 419419 are approximately 150-250 kDa, 250-300 kDa, and 340-360 kDa, respectively. These values are calculated based on the viscosity values provided on the product data sheets and the corresponding table of viscosity vs Mw.
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What are the Mark-Houwink–Sakurada parameters (K and alpha) you use for determination of molecular weight through viscosity? Thank you!
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The Certificates of Analysis(CofA) for each lot of Product 448869, a low molecular weight Chitosan, do not report a molecular weight. However, the viscosity in 1 percent acetic acid (abbreviated HAc or HOAc) is on the CofA. Values for K and alpha for high molecular weight Chitosan have been published, which might also apply to a low molecular weight Chitosan; see Calculation of Mark–Houwink–Sakurada (MHS) equation viscometric constants for chitosan in any solvent–temperature system using experimentally reported viscometric constants data, by Mohammed R. Kasaai. Carbohydrate Polymers, 68(3), 477-488 (2007).
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Is this analytical grade?
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This product is not considered analytical grade. It is intended for general research use. Currently, no analytical grade product option is available.
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Is it research or food grade? Thanks
1 answer-
This product is intended for research use only. Currently, there is no food-grade product option available
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what is the deacetylation percentage of this product?
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The minimum deacetylation percentage of this product will be 75 %. The value is lot-specific and reported on the Certificate of Analysis.
Please navigate to the bottom of the product detail page to the DOCUMENTATION section to download a sample Certificate.Helpful?
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Hi, I need to know the origin of this chitosan. It is from squid? Thanks
1 answer-
This product is sourced from the shells of Pandalus borealis, cold water shrimp.
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