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292206

Sigma-Aldrich

2-Methyl-1,3-dioxolane

97%

Synonym(s):

Acetaldehyde ethylene acetal

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MXP 803.00
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MXP 2,328.00

MXP 803.00

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5 G
MXP 803.00
25 G
MXP 2,328.00

About This Item

Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
497-26-7
Molecular Weight:
88.11
Beilstein:
102520
EC Number:
207-841-4
MDL number:
MFCD00003210
UNSPSC Code:
12352100
PubChem Substance ID:
24857568
NACRES:
NA.22

MXP 803.00

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Quality Level

100

Assay

97%

refractive index

n20/D 1.398 (lit.)

bp

82-83 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

functional group

ether

SMILES string

CC1OCCO1

InChI

1S/C4H8O2/c1-4-5-2-3-6-4/h4H,2-3H2,1H3

InChI key

HTWIZMNMTWYQRN-UHFFFAOYSA-N

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General description

The kinetics and mechanism of the gas-phase thermal decomposition of 2-methyl-1,3-dioxolane has been studied in a static system[1]. The infrared spectra of solid, liquid and gaseous 2-methyl-1,3-dioxolane has been studied[2]. Low-temperature ozonation of 2-methyl-1,3-dioxolane in acetone-d6, methyl acetate and tert-butyl methyl ether has been reported[3].

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H225

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

28.4 °F - closed cup

Flash Point(C)

-2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX2838
MKCW9757
MKCQ3944
MKCN3402
MKCL3102

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A Closse et al.
Naunyn-Schmiedeberg's archives of pharmacology, 335(4), 372-377 (1987-04-01)
Special conditions--tricine buffer containing Ca2+ and Mg2+, 22 degrees C (TCM)--allow to label a much higher proportion of muscarinic receptors by [3H]cis-methyldioxolane (CD) than hitherto described (Vickroy et al. 1984a). Taking the maximum number of binding sites, Bmax, of [3H]QNB
H I Yamamura et al.
Brain research, 325(1-2), 340-344 (1985-01-28)
(+)-cis-[3H]Methyldioxolane ((+)-[3H]CD), a potent muscarinic agonist, was used to label high-affinity agonist states of muscarinic receptors in thin tissue sections of the rat central nervous system. Light microscopic autoradiography of atropine-sensitive (+)-[3H]CD binding sites revealed regions of dense labeling (superior
E T Iwamoto et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 329-338 (1993-07-01)
The present study was designed to characterize the antinociception produced by the administration of a potent muscarinic agonist into the intrathecal space of the lumbar spinal cord of male Sprague-Dawley rats. Seven days after surgical implantation of intrathecal catheters, animals
R A Huff et al.
Journal of neurochemistry, 62(1), 388-391 (1994-01-01)
cis-Methyldioxolane (CD) is a muscarinic receptor agonist. [3H]CD has been used to label a subpopulation of muscarinic receptors described as exhibiting high agonist affinity. Pharmacological evidence suggests that the population of receptors labeled by [3H]CD consists of m2 and/or m4
M Watson et al.
Brain research, 346(2), 387-391 (1985-11-04)
The relationship of choline acetyltransferase (ChAT) activity and high affinity binding of the potent and selective sodium-dependent choline uptake inhibitor [3H]hemicholinium-3 ([3H]HC-3) to high-affinity binding of the muscarinic agonist [3H](+)-cis-methyldioxolane ([3H](+)CD), the putative M1 selective antagonist [3H]pirenzepine ([3H]PZ) and the
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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