183067
6-Methoxyquinoline
98%
Synonym(s):
6-Methoxyquinoline
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25 G
MXP 2,604.00
100 G
MXP 8,455.00
About This Item
Empirical Formula (Hill Notation):
C10H9NO
CAS Number:
Molecular Weight:
159.18
Beilstein:
115244
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
refractive index
n20/D 1.625 (lit.)
bp
140-146 °C/15 mmHg (lit.)
mp
18-20 °C (lit.)
density
1.15 g/mL at 20 °C (lit.)
SMILES string
COc1ccc2ncccc2c1
InChI
1S/C10H9NO/c1-12-9-4-5-10-8(7-9)3-2-6-11-10/h2-7H,1H3
InChI key
HFDLDPJYCIEXJP-UHFFFAOYSA-N
Gene Information
human ... CYP2D6(1565)
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Application
6-Methoxyquinoline is used as a precursor in the synthesis of:
- Fluorescent zinc and chlorine sensors.[1][2]
- 5-Amino-2-aroylquinolines as potent tubulin polymerization inhibitors.[3]
- 3-Fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase.[4]
- Cobalt-based ternary metal-organic complex as single?ion magnets.[5]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
>230.0 °F
Flash Point(C)
> 110 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
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Journal of Medicinal Chemistry, 54(24), 8517-8525 (2011)
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Single-Ion Magnets Based on Mononuclear Cobalt (II) Complexes with Sulfadiazine.
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European Journal of Inorganic Chemistry, 2016(29), 4835-4841 (2016)
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Human neutrophils synthesize hypochlorous acid, a nonradical oxidant, as one of the antimicrobial agents to kill phagocytosed pathogens within phagolysosomes. The production of HOCl is catalyzed by myeloperoxidase using chloride anions (Cl-). Even though various approaches have been documented to
Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
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