Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

143634

Sigma-Aldrich

p-Tolyl isocyanate

99%

Synonym(s):

4-Methylphenyl isocyanate

Sign Into View Organizational & Contract Pricing

Select a Size

5 G
MXP 1,012.00
25 G
MXP 1,507.00
100 G
MXP 5,127.00

MXP 1,012.00

Check Cart for Availability
Request a Bulk Order
All Photos(2)

Select a Size

Change View
5 G
MXP 1,012.00
25 G
MXP 1,507.00
100 G
MXP 5,127.00

About This Item

Linear Formula:
CH3C6H4NCO
CAS Number:
622-58-2
Molecular Weight:
133.15
Beilstein:
471494
EC Number:
210-743-4
MDL number:
MFCD00002029
UNSPSC Code:
12352100
PubChem Substance ID:
24848599
NACRES:
NA.22

MXP 1,012.00

Check Cart for Availability
Request a Bulk Order

Quality Level

100

Assay

99%

form

liquid

refractive index

n20/D 1.531 (lit.)

bp

70-72 °C/10 mmHg (lit.)

density

1.056 g/mL at 25 °C (lit.)

functional group

isocyanate

storage temp.

2-8°C

SMILES string

Cc1ccc(cc1)N=C=O

InChI

1S/C8H7NO/c1-7-2-4-8(5-3-7)9-6-10/h2-5H,1H3

InChI key

MGYGFNQQGAQEON-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

p-Tolyl isocyanate reacts with human serum albumin to form antigen which helps in detecting IgE antibodies in workers hypersensitive to toluene diisocyanate[1].

Application

p-Tolyl isocyanate was used to study the catalytic role of supported Rhodium(I) complex toward the reductive carbonylation of nitrobenzene in DMF medium[2].

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

150.8 °F - closed cup

Flash Point(C)

66 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW0033
MKCV3566
MKCQ8203
MKCQ3895
MKCN7841

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

B T Butcher et al.
The Journal of allergy and clinical immunology, 70(4), 231-235 (1982-10-01)
Toluene diisocyanate (TDI) sensitivity accompanied by nonspecific bronchial hyperresponsiveness occurs in approximately 5% of occupationally exposed workers. We report the case of a 32-yr-old worker followed longitudinally after removal from isocyanate exposure. TDI reactivity was lost 11 mo after removal
J M Danks et al.
Clinical allergy, 11(2), 161-168 (1981-03-01)
Radioallergosorbent testing was used to look for the presence of specific IgE antibody against a para-tolyl-mono-isocyanate human serum albumin conjugate in sera from five groups of subjects. The first three groups consisted of individuals exposed to toluene diisocyanate (TDI) who
Immunologic sensitization and pulmonary hypersensitivity by repeated inhalation of aromatic isocyanates.
M H Karol et al.
Toxicology and applied pharmacology, 53(2), 260-270 (1980-04-01)
[Technology of producing p-toluene isocyanate (C6H4CH3NCO) and a human albumin complex for clinical purposes].
E Sieradzki et al.
Acta poloniae pharmaceutica, 44(2), 237-241 (1987-01-01)
B T Butcher et al.
Clinical allergy, 13(1), 31-34 (1983-01-01)
Sera from 149 occupationally exposed toluene diisocyanate (TDI) workers were tested by RAST with p-tolyl monoisocyanate human serum albumin (TMI-HSA). Of the seven positives, one had a history suggestive of TDI asthma and one had a rash which may have
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service