LEF1
lymphoid enhancer-binding factor 1
Synonyms:
LEF-1, TCF10, TCF1ALPHA, TCF7L3
Species:
Human LEF1 (51176), Mouse Lef1 (16842), Rat Lef1 (161452), domestic guinea pig Lef1 (100716066), naked mole-rat Lef1 (101711023), dog LEF1 (478507), Zebrafish lef1 (30701), domestic cat LEF1 (101088077), cow LEF1 (535399), chicken LEF1 (395865)
UniProtKB ID:
Gene ID:
- Human(51176) Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(16842) lymphoid enhancer binding factor 1
- Rat(161452) lymphoid enhancer binding factor 1
- domestic guinea pig(100716066) lymphoid enhancer-binding factor 1
- naked mole-rat(101711023) lymphoid enhancer-binding factor 1
- dog(478507) lymphoid enhancer-binding factor 1
- Zebrafish(30701) lymphocyte enhancer binding factor 1
- domestic cat(101088077) lymphoid enhancer-binding factor 1
- cow(535399) lymphoid enhancer-binding factor 1
- chicken(395865) lymphoid enhancer-binding factor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
LEF1 (EP310) Rabbit Monoclonal Primary Antibody, ,
Species Reactivity
Application
immunohistochemistry
Monoclonal Anti-LEF-1 (β-Catenin binding domain) antibody produced in mouse, clone REMB1, ~1 mg/mL, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-LEF-1 (HMG DNA Binding Domain) antibody produced in mouse, ~1 mg/mL, clone REMB6, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-LEF1 Antibody, clone 9I9T4, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species