SAB4502354

Anti-PKC α antibody produced in rabbit

affinity isolated antibody

• Synonym(s): KPCA, PKC III, PKC-α, PKC-A, kinase PKC-α
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 76 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P17252
• UniProt accession no.: P17252
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PRKCA(5578)

Description

General description

Anti-PKC α Antibody detects endogenous levels of total PKC α protein.

PKC α (protein kinase C α) gene is mapped to 17q24.2. PKC α is expressed in heart, liver, brain and epithelium.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC alpha.

Immunogen Range: 606-655

Biochem/physiol Actions

PKC (protein kinase C) is known to mediate different cellular processes, such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. While PKC is also associated with the learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC α (protein kinase C α) being one of the isozymes of the PKC family, it catalyzes the phosphorylation of substrates with many peptides.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable