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61716

Sigma-Aldrich

4-Nitrophenyl dodecanoate

≥98.0% (GC)

Synonym(s):

4-Nitrophenyl laurate, Dodecanoic acid 4-nitrophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C18H27NO4
CAS Number:
Molecular Weight:
321.41
Beilstein:
1889084
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

Quality Level

Assay

≥98.0% (GC)

mp

~46 °C

solubility

chloroform: 1 g/10 mL, clear, colorless to faintly greenish-yellow

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C18H27NO4/c1-2-3-4-5-6-7-8-9-10-11-18(20)23-17-14-12-16(13-15-17)19(21)22/h12-15H,2-11H2,1H3

InChI key

YNGNVZFHHJEZKD-UHFFFAOYSA-N

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Application

4-Nitrophenyl dodecanoate has been used as a substrate:
  • for carboxylesterase to assess the enzyme-substrate affinity
  • in a chromogenic assay to evaluate lipase activity
  • to determine the esterase activity of patatin

Biochem/physiol Actions

4-Nitrophenyl dodecanoate is a p-nitrophenol ester derivative and serves as a typical model substrate in lipase assays.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T L R Corrêa et al.
Journal of applied microbiology, 115(1), 114-124 (2013-04-16)
In this study, a gene that encodes a carboxylesterase (carb) in Penicillium expansum GF was cloned, sequenced and overexpressed by Penicillium griseoroseum PG63, and the enzyme was characterized. The recombinant strain, P. griseoroseum T55, obtained upon transformation using the plasmid
P Fuciños et al.
Journal of biotechnology, 117(3), 233-241 (2005-05-03)
Thermus thermophilus HB27 produces important levels of extracellular lipolytic activity when grown for 30 h at 70 degrees C in a complex medium. A method to detect esterase activity in these samples after non-reducing SDS-polyacrylamide electrophoresis was developed. The method
Crosslinked, biodegradable polyurethanes for precision-porous biomaterials: synthesis and properties
Calleros EL, et al.
Journal of Applied Polymer Science, 48943 null
Chemical characterization and functional properties of a potato protein concentrate prepared by large-scale expanded bed adsorption chromatography
Lokra S, et al.
LWT--Food Science and Technology, 1089-1099 null
M Elleder et al.
Virchows Archiv. A, Pathological anatomy and histopathology, 416(4), 357-365 (1990-01-01)
An extremely benign variant of cholesterol ester storage disease (CESD) was diagnosed in two female patients aged 43 and 56 years. In one of them the course was entirely subclinical until a stroke at the age of 47, most probably

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