N-Ethyldiisopropylamine (EDIA) reacts with monoactivated Michael acceptors to afford symmetrical sulfones.[1]
Application
N,N-Diisopropylethylamine (DIPEA), also known as Hünig′s base, is a sterically hindered amine. It is commonly employed as a base in peptide synthesis. Additionally, DIPEA is also used in the Pd-catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.
Journal of colloid and interface science, 339(1), 266-270 (2009-08-15)
This paper describes the preparation of two-dye-doped silica nanoparticles for ratiometric pH measurements in the biologically relevant pH-range. While a rhodamine derivative is embedded in a silica core and used as the reference, a pH-sensitive naphthalimide dye is immobilized on
We present a silicon chip-based approach for the enhanced sensitivity detection of surface-immobilized fluorescent molecules. Green fluorescent protein (GFP) is bound to the silicon substrate by a disuccinimidyl terephtalate-aminosilane immobilization procedure. The immobilized organic layers are characterized by surface analysis
Journal of the American Society for Mass Spectrometry, 2(2), 168-173 (1991-04-01)
An automatic reaction control chemical ionization technique in an ion trap detector (lTD) was used to quantitate the levels of the cholinergic drug, arecoline, in plasma of treated patients with Alzheimer's disease. The chemical ionization reaction was carried out with
The Journal of biological chemistry, 280(35), 31208-31219 (2005-06-25)
(R)-Roscovitine (CYC202) is often referred to as a "selective inhibitor of cyclin-dependent kinases." Besides its use as a biological tool in cell cycle, neuronal functions, and apoptosis studies, it is currently evaluated as a potential drug to treat cancers, neurodegenerative
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