HCMBMAG-22K
MILLIPLEX® Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay
Circulating Cancer and Metastasis Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
About This Item
Quality Level
species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 70-105%
standard curve range: 0,019-80 ng/mL
(TRAP5)
standard curve range: 0,048-20 ng/mL
(YKL40)
standard curve range: 0.002-10 ng/mL
(GDF15)
standard curve range: 0.007-30 ng/mL
(DKK-1)
standard curve range: 0.007-30 ng/mL
(OPG)
standard curve range: 0.036-150 ng/mL
(NSE)
standard curve range: 0.195-800 ng/mL
(Periostin)
standard curve range: 0.976-4,00 0 ng/mL
(Osteonectin (SPARC))
inter-assay cv: <16%
intra-assay cv: <10%
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
General description
Metastasis is a complex process in which tumor cells leave the primary tumor site and migrate to other parts of the body via blood and lymph vessels or by tumor invasion of surrounding tissues and organs. Breaking away from the primary tumor, cancer cells attach to and degrade extracellular matrix proteins that separate tumor from surrounding tissues to escape into the stroma. Where metastases form often depends on the primary tumor. Bone metastases, for example, tend to arise from breast, prostate and kidney tumors. This organ/tissue specificity seems to involve chemical signals from both chemokines and growth factors.
Panel Type: Circulating Cancer
Application
- Analytes: DKK-1, GDF-15, Neuron-specific Enolase (NSE), Osteonectin (SPARC), Osteoprotegerin (OPG), Periostin, TRAP5, TWEAK, YKL40 (CHI3L1)
- Recommended Sample Type: Human serum, plasma, and tissue/cell culture supernatants or lysates
- Recommended Sample Dilution: 25 μL of 1:10 diluted serum or plasma; tissue/cell culture supernatants or lysates diluted may be diluted as needed in appropriate control medium
- Assay Run Time: Overnight (16-18 hours) at 2-8°C
- Research Category: Cancer
Features and Benefits
Other Notes
Legal Information
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificates of Analysis (COA)
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