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Key Documents

L060080

Sigma-Aldrich

Oxidizer

0.02 M, configured for PerkinElmer, configured for Polygen

Synonym(s):

Oxidizer

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About This Item

MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

type

for DNA synthesis

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

concentration

3.9-4.7 g/L (Iodine content, titration)

technique(s)

DNA synthesis: suitable

color

clear, brownish solution

bp

65—115 °C/1,013  hPa

compatibility

configured for PerkinElmer
configured for Polygen

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General description

Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine, and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor. The product configured for PerkinElmer and Polygen belongs to Expedite Formulation.

Preparation Note

Tetrahyrofurane/Water/Pyridine/Iodine 90.54/9.05/0.41/0.43 (v/v/v/w)

Legal Information

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-2.0 °F - closed cup

Flash Point(C)

-18.9 °C - closed cup


Certificates of Analysis (COA)

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