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Merck

1228530

USP

Dronedarone hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-{2-Butyl-3-[4-(3-dibutylaminopropoxy)benzoyl]benzofuran-5-yl}methanesulfonamide hydrochloride, Multaq, SR-33589B

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About This Item

Empirical Formula (Hill Notation):
C31H44N2O5S · HCl
CAS Number:
Molecular Weight:
593.22
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

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grade

pharmaceutical primary standard

API family

dronedarone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c2c(CCCC)oc3ccc(NS(C)(=O)=O)cc23

InChI

1S/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H

InChI key

DWKVCQXJYURSIQ-UHFFFAOYSA-N

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1 of 4

This Item
20832971289S8032
Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

powder

form

crystals

form

powder or crystals

mp

210 °C (lit.)

mp

210 °C (lit.)

mp

-

mp

370-425 °C

bp

400 °C (lit.)

bp

400 °C (lit.)

bp

-

bp

-

greener alternative product characteristics

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greener alternative product characteristics

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greener alternative product characteristics

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greener alternative product characteristics

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dronedarone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Dronedarone Tablets

Biochem/physiol Actions

Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Hazard Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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