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Key Documents

SCP0139

Sigma-Aldrich

Caspase 8 Substrate, fluorogenic

≥95% (HPLC), lyophilized

Synonym(s):

Ac-VETD-AMC

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About This Item

Empirical Formula (Hill Notation):
C30H39N5O12
Molecular Weight:
661.66
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Caspase 8 Substrate, fluorogenic,

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥67%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP8(841)

Amino Acid Sequence

Ac-Val-Glu-Thr-Asp-AMC

Application

Fluorogenic caspase 8 substrate has been used to measure caspase 8 activity in Jurkat cell lysates.

Biochem/physiol Actions

The peptide Ac-Val-Glu-Thr-Asp-AMC, or Ac-VETD-AMC, is a fluorogenic, modified peptide substrate for caspase 8.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T L Yue et al.
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Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous lipids. However, the data on the biological activity of acylcholines remain very limited. We hypothesized that acylcholines containing residues of arachidonic (AA-CHOL), oleic (Ol-CHOL), linoleic (Ln-CHOL), and

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