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S6814

Sigma-Aldrich

SynaptoGreen™ C4

≥95% purity (HPLC), solid

Synonym(s):

FM1-43, N-(3-triethylammoniumpropyl) -4-(4-(dibutylamino)styryl) pyridinium dibromide, Pyridinium, 4-[2-[4-(dibutylamino)phenyl]ethenyl]- 1-[3-(triethylammonio)propyl]- , dibromide

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About This Item

Empirical Formula (Hill Notation):
C30H49Br2N3
CAS Number:
149838-22-2
Molecular Weight:
611.54
MDL number:
MFCD00467815
UNSPSC Code:
12171500
PubChem Substance ID:
329824569
NACRES:
NA.47

product name

SynaptoGreen™ C4, ≥95% (HPLC), solid

Quality Level

100

Assay

≥95% (HPLC)

form

solid

color

dark red

solubility

DMSO: soluble
H2O: soluble

εmax

≥50000 at 507-513 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[Br-].[Br-].CCCCN(CCCC)c1ccc(\C=C\c2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1

InChI

1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5;;/h14-21,25-26H,6-13,22-24,27H2,1-5H3;2*1H/q+2;;/p-2

InChI key

VZUVCAGXYLMFEC-UHFFFAOYSA-L

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General description

SynaptoGreen™ C4 is an oxonol dye that helps in the rapid detection of an antibiotic′s effect on bacterial viability. It is a fluorescent dye that is used in optical imaging studies to determine synaptic activity by staining synaptic vesicles at the nerve terminal or the neuromuscular junction. It is equivalent to FM1-43.

Application

SynaptoGreen™ C4 has been used to label cultured neurons grown on EM grids for fluorescent labeling, live light microscopy and imaging studies.

Biochem/physiol Actions

A fluorescent nerve terminal dye suitable for monitoring synaptic activity at synapses and at neuromuscular junctions.

Other Notes

Component of NTSI, also sold individually.

Legal Information

SynaptoGreen is a trademark of Biotium, Inc.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCS0312
MKCR1784
MKCQ0878
MKCK9991
MKCK5858

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We investigated the phylogenetic diversity, localisation and metabolism of an uncultured bacterial clade, Termite Group 2 (TG2), or ZB3, in the termite gut, which belongs to the candidate phylum 'Margulisbacteria'. We performed 16S rRNA amplicon sequencing analysis and detected TG2/ZB3
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