Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, (120)(120), 98-100 (2003-03-18)
2-(2'-hydroxy-5'-methylphenyl)-benzotriazole (HMB) is nominated as the restricted ingredients in cosmetics in Japanese Pharmaceutical Affairs Act. So the analytical method for HMB was investigated by HPLC. After dissolving HMB in cream or oil with tetrahydrofuran and making the constant volume with
The contact sensitizing potential of 2-(2'-hydroxy-5'-methylphenyl)benzotriazole (Tinuvin P) was investigated using the murine local lymph node assay (LLNA) and the mouse ear swelling test with some modification in the induction procedure (modified MEST). Topical exposure of the ears to Tinuvin
We report a 54-year-old female with allergic contact dermatitis from 2-(2-hydroxy-5-methylphenyl)benzotriazole (Tinuvin P) in a spandex tape sewn into underwear. Tinuvin P is used as an ultraviolet light absorber for stabilizing plastics and the other organic materials against discoloration and
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