305251

(S)-(−)-2-(Trifluoroacetamido)succinic anhydride

97%

• Synonym(s): (S)-(−)-2-Trifluoroacetamidosuccinic anhydride, N-Trifluoroacetyl-L-aspartic acid anhydride
• Empirical Formula (Hill Notation): C₆H₄F₃NO₄
• CAS Number: 777-33-3
• Molecular Weight: 211.10
• MDL number: MFCD00012332
• UNSPSC Code: 12352005
• PubChem Substance ID: 24858416
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• optical activity: [α]20/D −28.0°, c = 1 in THF
• mp: 131-132 °C (lit.)
• functional group: amide; anhydride; ester; fluoro
• SMILES string: FC(F)(F)C(=O)N[C@H]1CC(=O)OC1=O
• InChI: 1S/C6H4F3NO4/c7-6(8,9)5(13)10-2-1-3(11)14-4(2)12/h2H,1H2,(H,10,13)/t2-/m0/s1
• InChI key: ABTJOHYOWBAGTP-REOHCLBHSA-N

Description

Application

Useful in the synthesis of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, a potent dopamine agonist. Used in the synthesis of sweetening agents, such as N-trifluoroacetyl-L-aspartic acid α-amides and α-anilides.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300
• Precautionary Statements: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves