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253421

Sigma-Aldrich

3-(2-Iodoacetamido)-PROXYL

free radical

Synonym(s):

3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical

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About This Item

Empirical Formula (Hill Notation):
C10H18IN2O2
CAS Number:
27048-01-7
Molecular Weight:
325.17
MDL number:
MFCD00010161
UNSPSC Code:
12352101
PubChem Substance ID:
24855311
NACRES:
NA.22

form

solid

mp

162-164 °C (lit.)

functional group

amide
iodo

storage temp.

2-8°C

SMILES string

CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]

InChI

1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)

InChI key

OQIGMSGDHDTSFA-UHFFFAOYSA-N

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General description

3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.

Application

Sulfhydryl group specific spin label. Applications include study of ozone-treated human and bovine erythrocyte membrane proteins and the orientation of myosin subfragment on muscle fibers. DNA fragments containing phosphorothioate diesters can be labeled by spin labels.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000340971
0000242180
0000179169
BGBC1436V

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