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130532

Sigma-Aldrich

5,7-Dichloro-8-hydroxy-2-methylquinoline

98%

Synonym(s):

5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM

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About This Item

Empirical Formula (Hill Notation):
C10H7Cl2NO
CAS Number:
72-80-0
Molecular Weight:
228.07
Beilstein:
156683
EC Number:
200-789-3
MDL number:
MFCD00023984
UNSPSC Code:
12352100
PubChem Substance ID:
24847966
NACRES:
NA.22

Quality Level

200

Assay

98%

mp

108-112 °C (dec.) (lit.)

SMILES string

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

InChI key

GPTXWRGISTZRIO-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A double-blind comparative study to compare the efficacy of Locoid C with Tri-Adcortyl in children with infected eczema.
F O Meenan
The British journal of clinical practice, 42(5), 200-202 (1988-05-01)
I Corrihons et al.
Pathologie-biologie, 39(2), 136-139 (1991-02-01)
The activity of chlorquinaldol, a derivative of hydroxy-8-quinolein used for local antisepsy, was studied against Neisseria gonorrhoeae and Chlamydia trachomatis. The weak solubility of the product and the special growth conditions of the organisms made an adaptation of the AFNOR
M Miścicka et al.
Acta poloniae pharmaceutica, 47(3-4), 25-28 (1990-01-01)
Chromatographic conditions for the separation of five pairs of active compounds occuring in four ointment preparations and an aerosol one were elaborated. The ways of extraction of hydrocortisone esters (acetate and butyrate), chlorquinaldol, oxytetracycline base and oxytetracycline hydrochloride from the
A Neiger et al.
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 79(31-32), 918-920 (1990-08-02)
Besides the various operative procedures, which nowadays have come into use in hemorrhoidal disorders, drug therapy as well continues to keep an important place. Its main conditions of application are inflammatory processes before, between and after hemorrhoidal sclerosis or proctological
[Diflucortolone valerate and chlorquinaldol in topical eczema (in single or combination form)].
C Solaroli et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 122(5), XXXI-XXXIII (1987-05-01)
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