D1306

Debrisoquine sulfate

powder, ≥98% (TLC)

• Synonym(s): 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide, Debrisoquin sulfate, Ro 5-33071
• Linear Formula: C₂₀H₂₆N₆ · H₂SO₄
• CAS Number: 581-88-4
• Molecular Weight: 448.54
• EC Number: 209-472-4
• MDL number: MFCD00153791
• UNSPSC Code: 12352204
• PubChem Substance ID: 24277710
• NACRES: NA.32

Properties

• product name: Debrisoquine sulfate,
• Assay: ≥98% (TLC)
• Quality Level: 200
• form: powder
• mp: 285 °C
• solubility: H₂O: 20 mg/mL (with heat)
• storage temp.: room temp
• SMILES string: OS(O)(=O)=O.NC(=N)N1CCc2ccccc2C1.NC(=N)N3CCc4ccccc4C3
• InChI: 1S/2C10H13N3.H2O4S/c2*11-10(12)13-6-5-8-3-1-2-4-9(8)7-13;1-5(2,3)4/h2*1-4H,5-7H2,(H3,11,12);(H2,1,2,3,4)
• InChI key: CAYGYVYWRIHZCQ-UHFFFAOYSA-N
• Gene Information: human ... SLC6A2(6530)

Description

Biochem/physiol Actions

Debrisoquine is an anti-hypertensive agent. It is metabolized by cytochrome P4502D6.

Substrates

A substrate for cytochrome P450 CYP2D6; an indicator for genetic polymorphism in cytochrome P450.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves