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D7881

Sigma-Aldrich

meso-2,3-Dimercaptosuccinic acid

~98%

Synonym(s):

2,3-Dithio-meso-tartaric acid, DIM-SA, DMS, DMSA, Succimer

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About This Item

Linear Formula:
HO2CCH(SH)CH(SH)CO2H
CAS Number:
304-55-2
Molecular Weight:
182.22
Beilstein:
1725150
EC Number:
206-155-2
MDL number:
MFCD00064799
UNSPSC Code:
12352100
PubChem Substance ID:
57654130
NACRES:
NA.22

Assay

~98%

Quality Level

200

form

powder

mp

196-198 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

OC(=O)[C@@H](S)[C@@H](S)C(O)=O

InChI

1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+

InChI key

ACTRVOBWPAIOHC-XIXRPRMCSA-N

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Application

meso-2,3-Dimercaptosuccinic acid (DMSA) has been used to form a monolayer on Mg/Ti/Au micromotors to enhance the chelation of toxic heavy metal contaminants (Zn(II), Cd(II) and Pb(II)) from polluted aqueous solutions.
It can be used:
  • As a reducing and stabilizing agent to synthesize monolayer-protected gold clusters.
  • For terminal carboxylation of the oleylamine coated Fe3O4 nanoparticles, to develop targeted curcumin drug delivery system.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thanasis Chouliaras et al.
Membranes, 9(12) (2019-12-11)
Polymeric (ionic liquid) (PIL) copolymers bearing cationic imidazolium pendants and polar acrylic acid groups (P(VBCImY-co-AAx)), which both favor the interaction with CO2 molecules, have been synthesized and blended with film forming, high glass transition temperature aromatic polyether-based pyridinium PILs (PILPyr).
Francesca Brero et al.
Nanomaterials (Basel, Switzerland), 10(10) (2020-10-01)
A combination of carbon ions/photons irradiation and hyperthermia as a novel therapeutic approach for the in-vitro treatment of pancreatic cancer BxPC3 cells is presented. The radiation doses used are 0-2 Gy for carbon ions and 0-7 Gy for 6 MV
Hongyu Qiao et al.
Biomaterials, 112, 336-345 (2016-10-28)
Rupture of vulnerable atherosclerotic plaque is the major pathological cause of luminal thrombosis in acute coronary syndromes. Since foamy macrophages have been identified as a prominent component in vulnerable atherosclerotic lesions and osteopontin (OPN) is reported to be highly expressed
Bo Ae Yun et al.
Annals of laboratory medicine, 38(5), 425-430 (2018-05-26)
Urinary tract infection (UTI) is the most common bacterial infection in infants. Renal parenchymal involvement is an important prognostic factor; however, early detection of parenchymal involvement in UTI may be difficult during infancy. This study aimed to assess whether a
Erdinç Turk et al.
Biological trace element research, 189(1), 95-108 (2018-08-02)
The present study was conducted to investigate the protective effects of hesperidin (HSP) against sodium arsenite (SA)-induced nephrotoxicity and hepatotoxicity in rats. Thirty-five male Sprague Dawley rats were divided into five groups as follows: control, HSP, SA, SA + HSP 100, and
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