C0267

2-Chloroacetamide

≥98%

• Synonym(s): Chloracetamide, alpha-Chloroacetamide
• Linear Formula: ClCH₂CONH₂
• CAS Number: 79-07-2
• Molecular Weight: 93.51
• Beilstein: 878191
• EC Number: 201-174-2
• MDL number: MFCD00008027
• UNSPSC Code: 12352100
• PubChem Substance ID: 57653974
• NACRES: NA.22

Properties

• vapor pressure: 0.05 mmHg ( 20 °C)
• Quality Level: 300
• Assay: ≥98%
• form: powder
• mp: 116-118 °C (lit.)
• SMILES string: NC(=O)CCl
• InChI: 1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)
• InChI key: VXIVSQZSERGHQP-UHFFFAOYSA-N

Description

Application

2-Chloroacetamidecan be used as a reactant to synthesize:

• 2-Amino-4-chloroquinolines via o-alkylation of 4-chloro-1H-quinolin-2-ones and subsequent Smiles rearrangement.
• 2-(Formylaryloxy)acetamides by reacting with hydroxybenzaldehydes in the presence of potassium carbonate as a base.
• Biarylamine derivatives via aluminum triflate-catalyzed direct amination of benzhydrols.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H317,H361f
• Precautionary Statements: P202 - P261 - P264 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 338.0 °F
• Flash Point(C): 170 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves