Skip to Content
Merck
All Photos(2)

Documents

323594

Sigma-Aldrich

α-Hydroxyisobutyric acid

99%

Synonym(s):

alpha-Hydroxyisobutyric acid, 2-Hydroxy-2-methylpropionic acid, 2-Methyllactic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)2C(OH)COOH
CAS Number:
Molecular Weight:
104.10
Beilstein:
1744739
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

solid

bp

84 °C/1.5 mmHg (lit.)

mp

76-80 °C (lit.)

SMILES string

CC(C)(O)C(O)=O

InChI

1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6)

InChI key

BWLBGMIXKSTLSX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

α-Hydroxyisobutyric acid is a versatile building block in organic synthesis. It serves as a precursor in the synthesis of compounds like isobutylene glycol and methacrylic acid

Application

α-Hydroxyisobutyric acid (HIBA) can be used as:
  • A chelating agent to improve the separation of lanthanides and actinides by liquid chromatography.
  • In the synthesis of room temperature–stabilized, pure, nanocrystalline β-NiMoO4.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Electrospray ionization mass spectrometric studies on uranyl complex with α-hydroxyisobutyric acid in water-methanol medium
Jaison PG, et al.
Rapid Communications in Mass Spectrometry, 27(10), 1105-1118 (2013)
Bimetallic single-source precursor for the synthesis of pure nanocrystalline room temperature-stabilized β-NiMoO4
Moneeb AM, et al.
Ceramics International, 42(1), 1366-1372 (2016)
From rotational resolved spectra to an extended increment system of planar moments allowing ad-hoc conformational identification ? Exemplification by the broadband microwave spectrum of ??- hydroxyisobutyric acid
P Buschmann, et al.
Journal of Molecular Structure, 1250, 131805-131805 (2022)
Thore Rohwerder et al.
Microbial cell factories, 9, 13-13 (2010-02-27)
Nowadays a growing demand for green chemicals and cleantech solutions is motivating the industry to strive for biobased building blocks. We have identified the tertiary carbon atom-containing 2-hydroxyisobutyric acid (2-HIBA) as an interesting building block for polymer synthesis. Starting from
Y Shigematsu et al.
Pediatric research, 16(9), 771-775 (1982-09-01)
Organic acids in plasma and urine of a patient with isovaleric acidemia were measured serially during a severe ketoacidotic attack. Urinary ketone bodies, lactic acid and 2-hydroxy-n-butyric acid changed in parallel with the plasma isovaleric acid concentration, which was correlated

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service