SML3957

OSS_128167

≥98% (HPLC)

• Synonym(s): 5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid
• Empirical Formula (Hill Notation): C₁₉H₁₄N₂O₆
• CAS Number: 887686-02-4
• Molecular Weight: 366.32
• MDL number: MFCD07114226
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: N(c2cc(ccc2)C(=O)Nc3cc(c(cc3)O)C(=O)O)C(=O)c1[o]ccc1
• InChI: 1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)
• InChI key: HTJWLEGCECXGSQ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

eCll penetrant, potent and selective inhibitor of SIRT6.



OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable