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S7023

Sigma-Aldrich

Sera human

frozen liquid

Synonym(s):

Human Blood Serum, Human Serum

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

biological source

human

Quality Level

form

frozen liquid

origin

USA origin

shipped in

dry ice

storage temp.

−20°C

General description

The serum is the fluid from plasma devoid of fibrinogen, prothrombin, and other clotting factors. It contains various plasma proteins, amino acids, polypeptides, growth factors, fat, carbohydrates, nucleic acid derivatives, hormones, inorganic minerals, and vitamins.

Application

Sera human has been used:
  • to prepare the antigen standards for the validation assay of multiple-biomarker detection
  • as a quality check (QC) sample to optimize the experimental workflow
  • as a control in immunoproteomics assay

Biochem/physiol Actions

Human serum is used as a cell culture supplement. It maintains physiological balance by stimulating or inhibiting cell growth. It is known to have an inhibitory action on endogenous and exogenous enzymes.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Francesca L Short et al.
Infection and immunity, 88(8) (2020-06-10)
The serum complement system is a first line of defense against bacterial invaders. Resistance to killing by serum enhances the capacity of Klebsiella pneumoniae to cause infection, but it is an incompletely understood virulence trait. Identifying and characterizing the factors
Rhys A Dunstan et al.
Microbiology spectrum, 9(1), e0102321-e0102321 (2021-08-26)
The production of capsular polysaccharides by Klebsiella pneumoniae protects the bacterial cell from harmful environmental factors such as antimicrobial compounds and infection by bacteriophages (phages). To bypass this protective barrier, some phages encode polysaccharide-degrading enzymes referred to as depolymerases to
Kuiama Lewandowski et al.
The Journal of molecular diagnostics : JMD, 19(2), 303-312 (2017-01-04)
Extraction of viral RNA and the storage of sample material are extremely important factors in the detection and whole genome sequencing (WGS) of viral pathogens. Although PCR-based detection methods focus on small amplicons, viral WGS applications require RNA of high
Qin Fu et al.
Methods in molecular biology (Clifton, N.J.), 357, 365-371 (2006-12-19)
Serum is a readily available source for diagnostic assays, but the identification of disease-specific serum biomarkers has been impeded by the dominance of human serum albumin (HSA) and immunoglobulin G (IgG) in the serum proteome. Therefore, in order to observe
Josep Villanueva et al.
Nature protocols, 1(2), 880-891 (2007-04-05)
Blood is a convenient source of biomarkers. Readily obtainable, it immerses most tissues in the body and is therefore likely to contain cell-derived proteins and peptides that may provide information about various biological processes. Serum proteome and peptidome profiling--using mass

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