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Application
ProteoPrep® Blue Albumin & IgG Depletion Kit has been used:
- to deplete serum samples from immunoglobulin (Ig) G and albumin
- for albumin removal
- for albumin and IgG removal
- to deplete abundant plasma proteins for two-dimensional electrophoresis
Biochem/physiol Actions
ProteoPrep blue albumin depletion kit is designed to specifically remove albumin and IgG from 25 samples of human serum (25μL to 100μL) in preparation for two-dimensional electrophoresis (2DE). Albumin-depleted serum samples generated by this kit are in urea rather than salt-based buffers with little dilution, eliminating the need to precipitate the sample prior to performing 2DE.
Legal Information
ProteoPrep is a registered trademark of Merck KGaA, Darmstadt, Germany
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - STOT SE 1
Target Organs
Eyes,Central nervous system
Storage Class Code
3 - Flammable liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Anna Tomascova et al.
General physiology and biophysics, 38(4), 305-314 (2019-06-21)
Blood biomarkers are usually present in low concentration and can be masked by the high-abundance proteins, of which albumin is the predominant one. The purpose of this study was to compare four different albumin removal methods compatible with in-gel based
Zeyu Sun et al.
Theranostics, 9(4), 1200-1214 (2019-03-15)
Chronic HBV infection (CHB) can lead to acute-on-chronic liver failure (HBV-ACLF) characterized by high mortality. This study aimed to reveal ACLF-related proteomic alterations, from which protein based diagnostic and prognostic scores for HBV-ACLF were developed. Methods: Ten healthy controls, 16
Xi Liang et al.
Life science alliance, 4(10) (2021-08-26)
Sepsis is defined as an organ dysfunction syndrome and it has high mortality worldwide. This study analysed the proteome of serum from patients with sepsis to characterize the pathological mechanism and pathways involved in sepsis. A total of 59 patients
Yiting Li et al.
Methods in molecular biology (Clifton, N.J.), 818, 81-96 (2011-11-16)
The development of a sensitive, specific, and non-invasive approach for cancer detection will facilitate early detection and, hence, improve the outcome of individuals with known cancer predispositions. Proteomic profiling of blood emerges to be a logical choice of such non-invasive
Daxian Wu et al.
The Journal of clinical investigation, 130(4), 2069-2080 (2020-03-17)
BACKGROUNDHBV-related acute-on-chronic liver failure (HBV-ACLF) is hallmarked by high short-term mortality rates, calling for accurate prognostic biomarkers for initial risk stratification.METHODSThree tandem mass tag-labeled (TMT-labeled) quantitative proteomic studies were performed on 10 patients with HBV-related acute hepatic decompensation and on
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