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Key Documents

Y0001161

Carbasalate impurity B

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid, 2-Carboxyphenyl o-acetylsalicylate

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About This Item

Empirical Formula (Hill Notation):
C16H12O6
CAS Number:
530-75-6
Molecular Weight:
300.26
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

carbasalate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C16H12O6/c1-10(17)21-14-9-5-3-7-12(14)16(20)22-13-8-4-2-6-11(13)15(18)19/h2-9H,1H3,(H,18,19)

InChI key

DDSFKIFGAPZBSR-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carbasalate impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Hydrolysis of acetylsalicylsalicylic acid and salicylsalicylic acid in aqueous solution.
H Sunada et al.
Chemical & pharmaceutical bulletin, 33(5), 2158-2161 (1985-05-01)
Tamás Fischer
Orvosi hetilap, 150(11), 503-512 (2009-03-05)
The beneficial effect achieved by the treatment of endothelial dysfunction in chronic cardiovascular diseases is already an evidence belonging to the basic treatment of the disease. Given the fact that the vascular system is uniform and consubstantial both physiologically, pathophysiologically
P V Mroso et al.
Journal of pharmaceutical sciences, 71(10), 1096-1101 (1982-10-01)
Salicylsalicylic acid and acetylsalicylsalicylic acid were identified as decomposition products of aspirin when mixtures of the drug, with magnesium stearate, were stored in the solid state of 60 degrees and 75% relative humidity. The effect of increasing the concentration of
R D Kirchhoefer et al.
Journal of pharmaceutical sciences, 69(5), 550-553 (1980-05-01)
A quantitative high-pressure liquid chromatographic method, using a reversed-phase column and an aqueous acetic acid-methanol solution as the mobile phase, was employed for the determination of O-acetyl-O-salicylsalicylic acid and O-salicylsalicylic acid in pharmaceutical aspirin preparations. The aspirin was dissolved, filtered
F E Blondino et al.
Journal of pharmaceutical and biomedical analysis, 13(2), 111-119 (1995-02-01)
Formulation of pressurized aerosol solutions in propellants for inhalation requires the use of high quantities of surfactants to solubilize the drug. Due to the lipophilic nature of these surfactants, analytical difficulties are created for those wishing to quantify the drug
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