S1804

Trisodium citrate dihydrate

meets USP testing specifications

• Synonym(s): Sodium citrate tribasic dihydrate, Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
• Linear Formula: HOC(COONa)(CH₂COONa)₂ · 2H₂O
• CAS Number: 6132-04-3
• Molecular Weight: 294.10
• Beilstein: 6104939
• EC Number: 200-675-3
• MDL number: MFCD00150031
• UNSPSC Code: 12352300
• PubChem Substance ID: 24899497
• NACRES: NA.21

Properties

• Agency: meets USP testing specifications
• Quality Level: 300
• Assay: 99.0-100.5% anhydrous basis
• form: powder
• pH: 7.5-9 (25 °C, 29.4 g/L)
• mp: >300 °C (lit.)
• application(s): pharmaceutical (small molecule)
• SMILES string: O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
• InChI key: NLJMYIDDQXHKNR-UHFFFAOYSA-K

Description

Application

• Coumarin derivative-functionalized nanoporous silica as an on-off fluorescent sensor for detecting Fe(3+) and Hg(2+) ions: a circuit logic gate.: This study explores the utilization of Trisodium citrate dihydrate in the synthesis of nanoporous silica for the development of a fluorescent sensor. This sensor demonstrates potential applications in environmental monitoring and biomedical diagnostics, particularly for detecting hazardous metal ions (Mousavi et al., 2024).


• Silver Nanoparticles-Chitosan Nanocomposites: A Comparative Study Regarding Different Chemical Syntheses Procedures and Their Antibacterial Effect.: Research discusses the role of Trisodium citrate dihydrate in the synthesis of silver nanoparticles embedded in chitosan, emphasizing its efficacy in creating potent antibacterial agents suitable for various medical and industrial applications (Chicea et al., 2024).


• Improved production of andrimid in Erwinia persicina BST187 strain by fermentation optimization.: Demonstrates the application of Trisodium citrate dihydrate in optimizing fermentation processes to enhance the production of andrimid, a bioactive compound with significant pharmaceutical potential (Cheng et al., 2023).


• Fabrication of Ag nanostar and PEI-based SERS substrate for sensitive and rapid detection of SO(2): Application for detection of sulfite residues in beer.: Highlights the innovative use of Trisodium citrate dihydrate in the fabrication of specialized substrates for the rapid and sensitive detection of sulfite residues in beverages, underlining its importance in food safety and quality assurance (Kitaw et al., 2023).

Biochem/physiol Actions

Citrate is a intermediate in the TCA cycle and fatty acid synthesis. Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves