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I0050000

Idoxuridine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

5-Iodo-2′-deoxyuridine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil, 2′-Deoxy-5-iodouridine, 5-IUdR, IDU, IdUrd, Idoxuridine

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About This Item

Empirical Formula (Hill Notation):
C9H11IN2O5
CAS Number:
54-42-2
Molecular Weight:
354.10
Beilstein:
30397
MDL number:
MFCD00134656
UNSPSC Code:
41116107
PubChem Substance ID:
329815294
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

idoxuridine

manufacturer/tradename

EDQM

mp

194 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O

InChI

1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

InChI key

XQFRJNBWHJMXHO-RRKCRQDMSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Idoxuridine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H341,H361

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Therapeutics. XIV. Herpes simplex virus infections and idoxuridine.
H Ashton et al.
The British journal of dermatology, 84(5), 496-499 (1971-05-01)
Diane Alvarez et al.
Radiation research, 182(6), 607-617 (2014-11-20)
The goal of the current study was to measure the energy dependence of survival of rat 9L glioma cells labeled with iododeoxyuridine (IUdR) that underwent photon-activated Auger electron therapy using 25-35 keV monochromatic X rays, i.e., above and below the
Chirantani Mukherjee et al.
Nature communications, 10(1), 3287-3287 (2019-07-25)
Homologous recombination (HR) and Fanconi Anemia (FA) pathway proteins in addition to their DNA repair functions, limit nuclease-mediated processing of stalled replication forks. However, the mechanism by which replication fork degradation results in genome instability is poorly understood. Here, we
CURRENT STATUS OF CLINICAL INVESTIGATIONS WITH 6-AZAURIDINE, 5-IODO-2'-DEOXYURIDINE, AND RELATED DERIVATIVES.
P CALABRESI
Cancer research, 23, 1260-1267 (1963-09-01)
Danielle L Lavery et al.
Gut, 63(12), 1854-1863 (2014-02-20)
Barrett's oesophagus shows appearances described as 'intestinal metaplasia', in structures called 'crypts' but do not typically display crypt architecture. Here, we investigate their relationship to gastric glands. Cell proliferation and migration within Barrett's glands was assessed by Ki67 and iododeoxyuridine
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