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Supelco

Arsenic(III) oxide

reference material for titrimetry, certified by BAM, >99.5%

Synonym(s):

Arsenic trioxide, Arsenous acid

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About This Item

Empirical Formula (Hill Notation):
As2O3
CAS Number:
1327-53-3
Molecular Weight:
197.84
EC Number:
215-481-4
MDL number:
MFCD00003433
UNSPSC Code:
41116107
eCl@ss:
38080102
PubChem Substance ID:
329751594
NACRES:
NA.24

grade

reference material

Quality Level

100

Assay

>99.5%

quality

certified by BAM

technique(s)

titration: suitable

application(s)

agriculture
environmental

format

neat

SMILES string

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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General description

Arsenic(III) oxide is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content determination and homogeneity assessment are carried out using volumetric redox titration as the primary analysis method.

Application

The reference material is to be used as a reductometric standard for titer determinations in redox titrations.

Features and Benefits

  • Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • Traceable to NIST standard reference material
  • Offers accurate titer determinations
  • Accompanied by a certificate of analysis (CoA)

Analysis Note

Exact concentration, expiry date and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.

Signal Word

Danger

Hazard Statements

H300,H314,H350,H372,H410

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Target Organs

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

EU REACH Annex XIV (Authorisation List)

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8820
BCCB5135
BCCB3431
BCBT8539
BCBM3195V

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Michael Ash, Irene Ash
Handbook of Preservatives, 281 -281 (2004)
Arsenic?glutathione complexes?their stability in solution and during separation by different HPLC modes.
Raab, Andrea, et al.
Journal of Analytical Atomic Spectrometry, 19.1, 183-190 (2004)
Yuhua Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(1), 80-91 (2013-02-01)
Arsenic trioxide (As2O3) is a highly effective agent for treatment of acute promyelocytic leukemia (APL). However, consecutively administered As2O3 induces serious adverse cardiac effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Michael T Brady et al.
Leukemia research, 37(7), 822-828 (2013-05-01)
Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of approximately half of AML patients. We investigated the correlation between STAT3 activity, DC maturation and the ability to stimulate T-cells
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