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1048

Sigma-Aldrich

4-Nitrophenol

spectrophotometric grade

Synonym(s):

p-Nitrophenol

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About This Item

Linear Formula:
O2NC6H4OH
CAS Number:
100-02-7
Molecular Weight:
139.11
Beilstein:
1281877
EC Number:
202-811-7
MDL number:
MFCD00007331
UNSPSC Code:
12352102
eCl@ss:
39032018
PubChem Substance ID:
24846675
NACRES:
NA.21
Pricing and availability is not currently available.

grade

spectrophotometric grade

Quality Level

200

vapor pressure

0.6 mmHg ( 120 °C)

form

powder

autoignition temp.

541 °F

technique(s)

UV/Vis spectroscopy: suitable

bp

279 °C (lit.)

mp

110-115 °C (lit.)

solubility

ethanol: 95%, clear, dark yellow (100 mg/mL)

SMILES string

O=N(C1=CC=C(O)C=C1)=O

InChI

1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H

InChI key

BTJIUGUIPKRLHP-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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Application


  • Spectroscopic monitoring of polyurethane-based nanocomposite as a potential catalyst for the reduction of dyes.: This research explores the use of a polyurethane-based nanocomposite incorporating 4-Nitrophenol for spectroscopic monitoring and catalysis. The study demonstrates its effectiveness in reducing dye concentrations, providing a valuable tool for environmental cleanup and chemical processing industries (Alam K et al., 2024).

  • Silica@poly(chitosan-N-isopropylacrylamide-methacrylic acid) microgels: Extraction of palladium (II) ions and in situ formation of palladium nanoparticles for pollutant reduction.: Discusses the synthesis and application of innovative microgels that utilize 4-Nitrophenol in processes for extracting palladium ions and reducing pollutants. This highlights its utility in heavy metal remediation and nanoparticle synthesis, relevant for environmental and materials science (Alzahrani AYA et al., 2024).

  • Reaction mechanisms of chlorinated disinfection byproducts formed from nitrophenol compounds with different structures during chlor(am)ination and UV/post-chlor(am)ination.: Examines how 4-Nitrophenol and similar compounds react under different water treatment processes, providing insights into the formation and control of disinfection byproducts. This is crucial for improving water treatment safety and effectiveness (Prasad Singh R et al., 2024).

  • Comprehensive Studies of Adsorption Equilibrium and Kinetics for Selected Aromatic Organic Compounds on Activated Carbon.: This study provides a detailed analysis of 4-Nitrophenol adsorption on activated carbon, offering valuable data on its behavior in water treatment systems. The findings are critical for designing more efficient adsorption processes to remove contaminants from water (Marczewski AW et al., 2024).


Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H373

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 Oral

Target Organs

Kidney,Liver

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

336.2 °F - closed cup

Flash Point(C)

169.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBR0350
SHBN8992
SHBN8993
SHBN8994
SHBN6372

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A Mitrofanova et al.
Nature communications, 10(1), 2692-2692 (2019-06-21)
Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fluidity. Here we report that SMPDL3b excess, as observed in podocytes in diabetic kidney disease (DKD), impairs insulin receptor isoform B-dependent pro-survival insulin signaling by
Ali Mehdinia et al.
Journal of chromatography. A, 1283, 82-88 (2013-03-08)
In this study, an analytical procedure for the selective extraction and detection of 4-nitrophenol (4-NP) was investigated by using of molecularly imprinted polymer on the surface of magnetic nanoparticles (MNPs). The magnetic nanoparticles were modified by tetraethyl orthosilicate (TEOS) and
Alex V Birk et al.
The Journal of laboratory and clinical medicine, 140(3), 166-175 (2002-09-25)
Extracellular adenosine triphosphate (ATP) regulates platelet reactivity by way of direct action on platelet purinergic receptors or by hydrolysis to adenosine diphosphate (ADP). Subsequent metabolism of ATP and ADP to adenosine monophosphate (AMP) and adenosine inhibits platelet aggregation. Endothelial cell
Simon De Corte et al.
Colloids and surfaces. B, Biointerfaces, 102, 898-904 (2012-10-31)
An increasing demand for catalytic Pd nanoparticles has motivated the search for sustainable production methods. An innovative approach uses bacterial cells as support material for synthesizing Pd nanoparticles by reduction of Pd(II) with e.g. hydrogen or formate. Nevertheless, drawbacks of
Jau-Rung Chiou et al.
Journal of hazardous materials, 248-249, 394-400 (2013-02-19)
Silver/iron oxide composite nanoparticles have been synthesized successfully via a facile one-pot green route by the use of l-arginine, which created an aqueous solution of about pH 10 and acted as a reducing agent for the successive formation of iron
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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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