850340C
Avanti
13:0 PC
1,2-ditridecanoyl-sn-glycero-3-phosphocholine, chloroform
Synonym(s):
PC(13:0/13:0)
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About This Item
Empirical Formula (Hill Notation):
C34H68NO8P
CAS Number:
Molecular Weight:
649.88
UNSPSC Code:
51191904
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850340C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850340C
concentration
10 mg/mL (850340C-25mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
13:0 PC is ditridecanoyl phosphatidyl choline (DTPC). Phosphatidylcholine (PC) is a phospholipid, present in endothelial cells, corneal epithelial cells, and fibroblast. Structurally, PC has a polar head consisting of choline and phosphate and two non-polar tails consisting of fatty acids. The polar head group is water soluble and the non-polar tails are water insoluble. Due to its amphiphilic properties, it is present in the cell membrane. In the human body, liver synthesizes PC. Dietary sources of PC are egg and soybeans.
Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It can form strong bilayer and is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
13:0 PC (1,2-ditridecanoyl-sn-glycero-3-phosphocholine) may be used as a lipid standard for the quantification of phosphatidylcholines (PCs) by mass spectrometric analysis.
13:0 Phosphatidylcholine (PC) has been used as a lipid standard for mass spectrometry.
Biochem/physiol Actions
Phosphatidylcholine (PC) is the precursor for the triacylglycerol synthesis. The concentration of PC decreases owing to enhanced triacylglycerol production in the liver. Phosphatidylcholine may be a biomarker for the diagnosis of fatty liver. Its structure enables them to be used in food industry as emulsifiers.
Phosphatidylcholine (PC) can serve as a surfactant in the mucus.
Packaging
5 mL Clear Glass Sealed Ampule (850340C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Genea Edwards et al.
Biochimie, 101, 232-247 (2014-02-25)
To compare phospholipid (phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and phosphatidylinositol) profiles of human control and glaucomatous aqueous humor (AQH). AQH samples were procured during surgery from human POAG and control subjects (n = 15 each). Samples were used following institutional review board
Phospholipid makeup of the breast adipose tissue is impacted by obesity and mammary cancer in the mouse: Results of a pilot study
Margolis M, et al.
Biochimie, 108(11), 133-139 (2015)
Julie M Davies et al.
PloS one, 9(12), e114352-e114352 (2014-12-04)
Intake of saturated fat is a risk factor for ulcerative colitis (UC) and colon cancer. Changes in the microbiota have been implicated in the development of UC and colon cancer. The host and the microbiota generate metabolites that may contribute
Self-assembled phospholipid unilamellar vesicles
Liposomes, Part G (2009)
Membrane lipids:phospholipids
General, Organic, and Biological Chemistry, 108(11), 581-581 (2006)
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