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Key Documents

T7633

Sigma-Aldrich

Triethylenetetramine-N,N,N′,N′′,N′′′,N′′′-hexaacetic acid

for complexometry, ≥98.0%

Synonym(s):

TTHA

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About This Item

Linear Formula:
[-CH2N(CH2CO2H)CH2CH2N(CH2CO2H)2]2
CAS Number:
Molecular Weight:
494.45
Beilstein:
1811090
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

for complexometry

Quality Level

Assay

≥98.0%

form

powder

mp

232-233 °C (lit.)

SMILES string

OC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O

InChI

1S/C18H30N4O12/c23-13(24)7-19(3-5-21(9-15(27)28)10-16(29)30)1-2-20(8-14(25)26)4-6-22(11-17(31)32)12-18(33)34/h1-12H2,(H,23,24)(H,25,26)(H,27,28)(H,29,30)(H,31,32)(H,33,34)

InChI key

RAEOEMDZDMCHJA-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Agnieszka Gawin et al.
Scientific reports, 10(1), 12470-12470 (2020-07-29)
Bacterial alginate initially consists of 1-4-linked β-D-mannuronic acid residues (M) which can be later epimerized to α-L-guluronic acid (G). The family of AlgE mannuronan C-5-epimerases from Azotobacter vinelandii has been extensively studied, and three genes putatively encoding AlgE-type epimerases have
E Suzuki et al.
The Journal of laboratory and clinical medicine, 124(5), 627-637 (1994-11-01)
To define the existence of intracellular hydration caused by metabolic derangements in the excised sciatic nerves of diabetic rats quantitatively, relaxation times (T1, T2) and fraction of intracellular water content were measured with 1H-nuclear magnetic resonance (NMR) spectroscopy in normal
Belén Frígols et al.
PloS one, 14(3), e0212819-e0212819 (2019-03-08)
Alginate is considered an exceptional biomaterial due to its hydrophilicity, biocompatibility, biodegradability, nontoxicity and low-cost in comparison with other biopolymers. We have recently demonstrated that the incorporation of 1% graphene oxide (GO) into alginate films crosslinked with Ca2+ cations provides
M S Ali et al.
Bioconjugate chemistry, 7(5), 576-583 (1996-09-01)
Immunoconjugates sometimes suffer changes in immunoreactivity and tumor targeting because the chelators used interfere with antigen binding. To try to circumvent such problems, two new homobifunctional chelating agents, 2,6-bis[p-[(beta-maleimidopropionyl) amino]benzyl]diethylenetriamine- N,N,N',N",N"-pentaacetic acid (MPBz-DTPA) and 2,9-bis [p-(beta-maleimidopropionyl)amino]benzyl] triethylenetetraamine-N,N,N',N',N",N"-hexaacetic acid (MPBz-TTHA), were
R B Clarkson et al.
Magnetic resonance in medicine, 29(4), 521-527 (1993-04-01)
Electron Spin Echo Envelope Modulation (ESEEM) data are reported for three gadolinium (III) chelates, Gd-EDTA, Gd-DTPA, and Gd-TTHA, in frozen D2O/CH3OD glasses. This series includes Gd-DTPA, an MRI contrast agent that is in clinical use. Three-pulse electron spin echo modulation

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