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Key Documents

D17106

Sigma-Aldrich

2,7-Diaminofluorene

>97%

Synonym(s):

2,7-Fluorenediamine

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About This Item

Empirical Formula (Hill Notation):
C13H12N2
CAS Number:
Molecular Weight:
196.25
Beilstein:
2099859
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

>97%

form

powder

mp

160-162 °C (lit.)

SMILES string

Nc1ccc-2c(Cc3cc(N)ccc-23)c1

InChI

1S/C13H12N2/c14-10-1-3-12-8(6-10)5-9-7-11(15)2-4-13(9)12/h1-4,6-7H,5,14-15H2

InChI key

SNCJAJRILVFXAE-UHFFFAOYSA-N

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Application

Analytical reagent for metals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R E Worthington et al.
Experimental hematology, 15(1), 85-92 (1987-01-01)
We have developed a new colorimetric method to detect early erythroid clonogenic progenitor cells by virtue of their hemoglobin-containing progeny in vitro. The method relies upon the specific oxidation of 2,7-diaminofluorene (DAF) by the pseudoperoxidase activity of hemoglobin (Hb). Generation
T Ducrot et al.
Vox sanguinis, 71(1), 30-36 (1996-01-01)
The mechanism whereby passive Rh (D) immunoglobulins suppress the fetomaternal alloimmunization is still unclear. New in vitro tests are needed to better characterize the functional properties of polyclonal anti-Ds. The DAF assay was developed to monitor the antibody-dependent cell-mediated cytotoxicity
Daniel Trnka et al.
Nature communications, 11(1), 3445-3445 (2020-07-12)
Despite their very close structural similarity, CxxC/S-type (class I) glutaredoxins (Grxs) act as oxidoreductases, while CGFS-type (class II) Grxs act as FeS cluster transferases. Here we show that the key determinant of Grx function is a distinct loop structure adjacent
Rudy Chang et al.
Frontiers in cellular neuroscience, 12, 279-279 (2018-09-22)
Peripheral endothelial cells are capable of erythrophagocytosis, but data on brain endothelial erythrophagocytosis are limited. We studied the relationship between brain endothelial erythrophagocytosis and cerebral microhemorrhage, the pathological substrate of MRI-demonstrable cerebral microbleeds. To demonstrate the erythrophagocytic capability of the
R F Montaño et al.
Journal of immunological methods, 222(1-2), 73-82 (1999-02-18)
In this report we describe a reliable, sensitive, safe, and easy way to assess antibody-dependent complement-mediated hemolysis. The assay is based on the quantitation of hemoglobin (Hb) released from lysed erythrocytes indirectly, through the generation of fluorene blue, a compound

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