900919

Azidoacetic acid NHS ester

• Synonym(s): (2,5-Dioxopyrrolidin-1-yl) 2-azidoacetate, 1-[(Azidoacetyl)oxy]pyrrolidine-2,5-dione
• Empirical Formula (Hill Notation): C₆H₆N₄O₄
• CAS Number: 824426-32-6
• Molecular Weight: 198.14
• MDL number: MFCD24452499
• UNSPSC Code: 12352106
• NACRES: NA.22

Properties

• form: powder or crystals
• Quality Level: 100
• reaction suitability: reagent type: cross-linking reagent
• availability: available only in USA
• storage temp.: −20°C
• InChI: 1S/C6H6N4O4/c7-9-8-3-6(13)14-10-4(11)1-2-5(10)12/h1-3H2
• InChI key: FENNDBOWHRZLTQ-UHFFFAOYSA-N

Description

Application

Azidoacetic acid NHS ester is a simple azido-containing reagent with an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines at pH 7-9 forming a stable amide bond. The azide allows for chemoselective ligation with an alkyne or cyclooctyne. It is generally used to functionalize amines and amino acids with azidoacetyl groups. It is generally used in click chemistry applications.

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H242
• Precautionary Statements: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable