Skip to Content
Merck
All Photos(2)

Key Documents

900648

Sigma-Aldrich

Methoxy poly(ethylene glycol)-block-poly(ε-caprolactone)

2k-5k

Synonym(s):

mPEG-b-PCL, mPEG-PCL

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

form

powder

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

On the mechanism of formation of vesicles from poly(ethylene oxide)-block-poly(caprolactone) copolymers.
Adams DJ, et al.
Soft Matter, 5, 3086-3096 (2009)
Xu Wen Ng et al.
Journal of pharmaceutical sciences, 103(11), 3631-3640 (2014-09-17)
Despite the success that drug-eluting stents (DESs) have achieved for minimizing in-stent restenosis (ISR), the antirestenotic agents used in DES have been implicated in delayed endothelial healing and impairment of endothelial functions. Cenderitide (CD-NP) is a novel antiproliferation chimeric peptide
Xu Wen Ng et al.
Drug delivery and translational research, 5(5), 469-479 (2015-06-24)
Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage
Simple solvothermalsynthesis of hydrophobic magnetic monodispersed Fe3O4 nanoparticles.
Liu J, et al.
Mat. Res. Bul., 48(2), 416-421 (2013)
Bhuvana S Doddapaneni et al.
Journal of controlled release : official journal of the Controlled Release Society, 220(Pt A), 503-514 (2015-11-19)
Metastatic melanoma has a high mortality rate due to lymphatic progression of the disease. Current treatment is surgery followed by radiation and intravenous chemotherapy. However, drawbacks for current chemotherapeutics lie in the fact that they develop resistance and do not

Articles

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service