Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

704083

Sigma-Aldrich

Trifluoromethanesulfonic anhydride solution

1 M in methylene chloride

Synonym(s):

Perfluoromethanesulfonic anhydride solution, Triflic anhydride solution

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C2F6O5S2
CAS Number:
358-23-6
Molecular Weight:
282.14
MDL number:
MFCD00000408
UNSPSC Code:
12352101
PubChem Substance ID:
329762092
NACRES:
NA.22

form

liquid

concentration

1 M in methylene chloride

refractive index

n20/D 1.402

density

1.359 g/mL at 25 °C

functional group

fluoro
triflate

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8

InChI key

WJKHJLXJJJATHN-UHFFFAOYSA-N

Application

Catalyst for synthesis of Bacteroides fragilis zwitterionic polysaccharide Ai tetrasaccharide repeating unit via glycosylation

Reagent for stereoselective synthesis of mennosazide methyl uronate donors

Activator for direct glycosylation with anomeric hydroxy sugars
Trifluoromethanesulfonic anhydride solution is generally used to convert hydroxyl groups to triflic esters. It can be used to prepare triflic azide for azido amino acid synthesis.

Signal Word

Danger

Hazard Statements

H272,H314,H335,H336,H351

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW7482
MKCW3105
MKCT7130
MKCT6706
MKCP6205

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Building units for N-backbone cyclic peptides. 2. Synthesis of protected N-(ω-thioalkylene) amino acids and their incorporation into dipeptide units.
Bilan G and Gilon C
Tetrahedron, 51(38), 10513-10522 (1995)
Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics
Hanold L E, et al.
PLoS ONE, 10(3), e0118796-e0118796 (2015)
Tanja Peters et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 94, 141-146 (2014-09-06)
The [(18)F]fluoroethyl moiety has been widely utilized in the synthesis of (18)F-labelled compounds. The aim of this work was the reliable synthesis of [(18)F]FEtOTf with a novel strategy to increase the reactivity of the commonly used [(18)F]FEB and [(18)F]FEtOTos. [(18)F]FEtOTf
Tatsuya Higashi et al.
Journal of pharmaceutical and biomedical analysis, 117, 155-162 (2015-09-12)
The analysis of changes in the brain neurosteroid (NS) levels due to various stimuli can contribute to the elucidation of their physiological roles, and the discovery and development of new antipsychotic agents targeting neurosteroidogenesis. We developed methods for the differential
Surendra Vutti et al.
Chembiochem : a European journal of chemical biology, 16(5), 782-791 (2015-03-05)
Stable primary functionalization of metal surfaces plays a significant role in reliable secondary attachment of complex functional molecules used for the interfacing of metal objects and nanomaterials with biological systems. In principle, this can be achieved through chemical reactions either

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service