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47628

Sigma-Aldrich

Fmoc-Ile-OH

≥98.0% (T)

Synonym(s):

N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine, Fmoc-L-isoleucine

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About This Item

Empirical Formula (Hill Notation):
C21H23NO4
CAS Number:
71989-23-6
Molecular Weight:
353.41
Beilstein:
4716717
EC Number:
276-255-9
MDL number:
MFCD00037125
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651048
NACRES:
NA.26

Quality Level

100

Assay

≥98.0% (T)

form

solid

optical activity

[α]20/D −12±1°, c = 1% in DMF

reaction suitability

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp

145-147 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc
amine
carboxylic acid

storage temp.

2-8°C

SMILES string

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChI key

QXVFEIPAZSXRGM-DJJJIMSYSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3604
BCCH2286
BCCD7459
BCCD7457
BCCD5472

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Moise Ndao et al.
Langmuir : the ACS journal of surfaces and colloids, 34(29), 8678-8684 (2016-04-05)
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Karthik Nadendla et al.
Molecular pharmaceutics, 16(7), 2922-2928 (2019-05-24)
We have previously described the photoactivated depot (PAD) approach for the light-stimulated release of therapeutic proteins such as insulin. The aim of this method is to release insulin from a shallow dermal depot in response to blood glucose information, using
R Ashton Lavoie et al.
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
Stefan Eissler et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 757-762 (2017-06-22)
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters
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